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In humans, OCT1 is mainly expressed in the sinusoid membrane of hepatocytes, whereas in rodents, OCT1 is strongly expressed in the basolateral membrane of renal proximal tubule cells
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Side effects: Nausea, constipation, and occasional vomiting similar to existing GLP-1 therapies
Orforglipron is a once-a-day pill that acts on glucagonlike peptide 1 (GLP-1) receptors
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