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GLP-1 medications can cause gastrointestinal side effects like nausea, vomiting, or diarrhea, which can lead to dehydration
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But apart from its action on insulin, GIP is also believed to improve the bodys long-term lipid storage, such that it reduces fat accumulation in the skeletal muscles and organs.14 This dual activity is likely what accounts for tirzepatides superlative efficacy for weight loss in clinical studies
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