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Interestingly, reductions in bodyweight and HbA1 c were similar in patients with improvements in liver histology (responders) and those without (non-responders), suggesting that, beyond bodyweight reduction and improvement in glucose control, other mechanisms may be involved in the beneficial effects of liraglutide
When patients recognize weight regain or worsening glucose control after discontinuation, they often seek guidance on safely restarting treatment
Signaling pathways in obesity: mechanisms and therapeutic interventions
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