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metformin with or without SGLT2i in PIONEER 4
Patients using properly stored tirzepatide report consistent appetite reduction week to week and predictable weight loss trajectories
For someone who needs rapid results (perhaps before a surgery or due to obesity-related health complications), standard escalation makes more sense
Limited data exist specifically examining GLP-1 receptor agonist effects on male reproductive function, though improvements in metabolic health would theoretically benefit fertility
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