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10.1038/nri2062 111 TanJ.XuX.TongZ.LinJ.YuQ.LinY.et al (2015)
Those who reached goal on lower doses (5 or 7.5 mg) sometimes maintain on 2.5 mg, particularly if they have adopted high-protein diets and resistance training
Avoid strong exfoliating acids (like glycolic, lactic, or salicylic acid), low-pH Vitamin C (ascorbic acid), and retinoids
A recent clinical study further confirmed that NSW disrupts 24-hour rhythms of PER2, PER3, BMAL1, and ESR2 in PBMCs, impairs the inverse correlation between PER2 and BMAL1, and alters PER1 and ESR1 expression patterns, highlighting a misalignment in the peripheral circadian network associated with NSW schedules 212
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