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Semaglutide's gastrointestinal effects vary by product and dose: nausea (20-44%), vomiting (9-24%), and diarrhea (9-30%) according to FDA prescribing information
A study published by Diabetes, Obesity and Metabolism found that users regain most of their lost weight within a year of stopping the medication (Wilding et al.) Either due to the high cost or ongoing shortages, people are seeking alternatives to Ozempic and Wegovy, according to NBC
Of note, people with type 2 diabetes had a lower mean percentage weight loss at the 3-month mark compared with those without type 2 diabetes: 3.9% in those with type 2 diabetes vs 6.3% in those without type 2 diabetes
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