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Li D, Zhang Y, Xu L, et al
As a defined small molecule, 5-Amino-1MQ is a "tool compound" in the classical pharmacology sense useful for probing NNMT biology specifically
It is a single small aromatic molecule designed to be membrane-permeable, so in principle it can survive the gut and cross into cells
Certain proteins and peptides cross intestinal epithelium through transcytosis and other transport mechanisms
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