In this context, S.aureus secretes a set of proteases, such as aureolysin metalloprotease, V8 and SspA serine proteases, ScpA and SspB cysteine proteases, that induce endogenous serine proteases activity in keratinocytes, leading to degradation of proteins essential for barrier integrity, such as filaggrin, kallikrein and desmoglein [23]
These include neurodegenerative disorders, liver diseases, and inflammatory conditions because of their ability to scavenge free radicals and reduce oxidative damage
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