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Metformin shows the strongest potential, supporting its prioritization for targeted studies in people with diabetes who are at high risk of AD, and highlighting the importance of precision medicine in future prevention trials
Because they bypass gastrointestinal digestion and absorption limitations, injectable therapies may provide stronger and more consistent effects for many patients
However, the non- or slow biodegradability of pristine MSNs and MONs can lead to long-term retention in vivo, thus inducing possible toxicity risks
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