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For example, Angong Niuhuang Wan inhibits the accumulation of ROS and Fe 2+ and improves mitochondrial dysfunction and BBB structural integrity by activating the PPAR/AKT/GPX4 pathway, thereby enhancing neurological function in rats with ischemic stroke and reducing cerebral infarction volume
Mitochondrial endpoints include ATP/ADP ratio, membrane potential, oxygen-consumption rate, extracellular-acidification rate, and mitophagy markers [8, 31,32,33,34,35]
Shankar V, Wilhelmy J, Curtis EJ, Michael B, Cervantes L, Mallajosyula V, et al
Ipamorelin, a selective growth hormone secretagogue, stimulates the pulsatile release of growth hormone (GH), which can enhance metabolism and fat breakdown
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