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Additionally, monitoring for signs of mood changes, gastrointestinal distress, and other potential side effects is crucial to ensure patient safety and treatment efficacy
Patients losing weight rapidly (more than 1 to 2 pounds per week sustained over months) are at higher risk because the mechanical unloading signal to bone is more acute
It also has benefits that extend beyond weight loss, including improvement of cholesterol levels, and decreasing blood pressure in those with high blood pressure and those with cardiovascular disorders
Other randomized control trials show similar results, too, with the best results coming from supervised exercise exceeding the 150-minute/week guideline (Lundgren, 2021
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