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[20] [21] NICE guidance supports orlistat use as part of a comprehensive weight management programme for adults with a BMI of 28 kg/m or above with associated risk factors (such as type 2 diabetes or cardiovascular disease), or 30 kg/m or above without additional risk factors
however, antioxidants such as ascorbic acid provide protection against this photodegradation (40)
Midazolam has also been described as a risk factor for developing overt and covert HE.105 On the other hand, propofol is a drug that can be used as a sedative in endoscopy and is not known to have pharmacokinetic differences in patients with kidney failure or liver failure
Why This Question Matters Patients with breast cancer who also have obesity or type 2 diabetes often face worse outcomes than those without these metabolic conditions
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