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One placebo-controlled trial, called ATTAIN-MAINTAIN, followed adults who had previously completed the SURMOUNT-5 obesity trial, a randomized controlled study evaluating whether tirzepatide, the active ingredient in Zepbound, led to greater body weight reduction versus semaglutide in adults with obesity

The strategy of repurposing medications for new uses is not only a promising approach for modern medicine, but also supports the validity of the integrative physiological approach to evaluating the overall health of an individual