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According to NICE Clinical Knowledge Summary guidance, patients with neurological involvement should receive more intensive initial treatment to optimise recovery potential
Precursor Nicotinamide Mononucleotide (NMN) Dose 300-900 mg Frequency Daily Trial signal 60-day dose-response RCT showed dose-dependent NAD+ rise
The April 15, 2026 removal from Category 2 was procedural
(2021) Vitamin B12 supplementation in diabetic neuropathy: a 1-year, randomized, double-blind, placebo-controlled trial
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