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The biogenesis of new proteins, which is one mechanism of maintaining proteostasis, can be evaluated in vivo by providing animals with deuterium oxide (heavy water, D 2 O) in drinking water and then measuring the incorporation of deuterium into proteins via GCMS methodology
Now, if that doesnt deter you, then the next question becomes how to administer NAD or its precursors: oral supplements, subcutaneous injections, or IV infusions
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