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Obesity as a Public Health Crisis and Contemporary Therapies Between 2021 and 2023, the prevalence of obesity, defined as a body-mass index (BMI, weight in kilograms divided by square of height in meters) 30, in adults in the United States increased to 40.3%, with no significant differences between men and women [6]

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Retatrutide is a 26-amino acid triple agonist that adds glucagon receptor activation to those two pathways

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