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That analysis came from a relatively small subpopulation of just 55 patients who underwent whole-body MRI scanning, which showed that the reduction in lean muscle mass with treatment, which raises concerns about loss of physical strength, mobility, and metabolic health, was around 10%
doi:10.4239/wjd.v5.i4.444 8
Nuttall et al.[37] studied the effect of chronic ingestion of therapeutic doses of APAP (1 gram, 4 times per day, for 2 weeks) on serum antioxidant capacity, and found a gradual and progressive decline to a level about 85% of control value
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