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The AAFPs evidence-based clinical review states directly: Oral administration of high-dose vitamin B12 (1 to 2 mg daily) is as effective as intramuscular administration for correcting anemia and neurologic symptoms in patients with B12 deficiency (Langan RC, Goodbred AJ, American Family Physician, 2017)
Several theories explain why headaches occur
Research suggests the use of vitamin B12 supplements in those with kidney disease and a B12 deficiency, but fully understanding the risks and benefits of regular supplemental B12 in those without a deficit still requires more research
It works on brain chemicals like dopamine, norepinephrine, and serotonin, helping users feel fuller faster and for longer
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