Initially, when insulin resistance occurs, pancreatic bcells compensate by secreting more insulin to maintain normal glucose metabolism, but as the disease progresses, pancreatic b cell function deteriorates, insulin secretion significantly decreases, blood sugar cannot return to normal baseline levels, leading to metabolic disorders, including glucose and lipid abnormalities, and metabolic diseases such as T2DM (Warram et al., 1990
It comes in both injectable (Ozempic, Wegovy pen) and oral (Rybelsus, Wegovy pill) forms
Liraglutide has been studied extensively since 2010
After that, the glucose supplies your body with the necessary energy to live through the day