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We dont yet fully understand the long-term side effects, or how best to sustain weight loss over time

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Retatrutide may become the preferred option for patients who need more aggressive weight management or who have specific conditions like fatty liver disease that benefit from glucagon receptor activation

For each cell population and gene set, a linear mixed-effects model was constructed with the gene set activity as the dependent variable, treatment and time point as independent variables with interaction effects, and mouse and sequencing pool as random effects