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Heart failure therapy by GLP-1RAs Although a meta-analysis of large-scale clinical trials suggested that GLP-1RAs reduce heart failure hospitalizations (HHF) by approximately 10% in patients with diabetes at high cardiovascular risk [22, 23], the treatment effects on the risk of HHF in individual trials other than AMPLITUDE-O were not significant (Tables 1, 2)
Studies have shown that exposure to H 2 O 2 causes mouse auditory HCs to prematurely exhibit a senescence-like phenotype [95]
The doses reported below are from published literature and do not constitute a current dosing recommendation
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