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Decongestants (pseudoephedrine, phenylephrine) can raise heart rate and blood pressure, which combines additively with the small heart rate increase from tirzepatide
Here's a rough timeline (results vary): Week 12: Most adjustment symptoms, including fatigue, are common Week 34: Many people start feeling more like themselves Month 2+: Energy levels often improve as the body adapts Keep in mind: results vary from person to person
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More serious concerns, pancreatitis and thyroid tumors, have been flagged, mostly from animal studies, and your provider should screen your personal history before prescribing
