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Proteins that regulate ferroptosis are GPX4 (glutathione peroxidase 4), cystine/glutamate antiporter System Xc, iron homeostasis, and some enzymes associated with lipids synthesis such as (Acyl-CoA Synthetase Long Chain Family Member 4 (ACSL4) and Lysophosphatidylcholine Acyltransferase 3 (LPCAT3) [249, 250]
Presented for research literature review only Sizova ZM et al
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We tested this hypothesis by injecting Cre-dependent Gsto2 -short hairpin RNA (shRNA) or a scrambled-shRNA viral construct in the striatum of Trkb Penk -KO mice to allow expression of the shRNA specifically in enkephalinergic neurons at 3 months (Fig
