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As SPHKAP has previously been shown to bind to the mitochondrial cristae junction regulator and MICOS complex component MIC19 29 , a prominent PKA substrate involved in both cristae assembly during mitochondrial remodelling 43 and regulation of ERMCSs 11 , we next tested whether exendin-4 stimulation would trigger MIC19 phosphorylation in WT INS-1 832/3 cells using a MIC19 immunoprecipitation strategy coupled with Western blotting with an antibody raised against PKA phosphosites (RRxpS/T) 44
After propensity score matching, the analytic cohort comprised 26,408 matched patients: 13,204 users and 13,204 non-users
Higgins JPT, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, Welch VA
Brain regulation of appetite and satiety
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