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Key distinctions matter because they guide evaluation: a globus sensation without difficulty swallowing or breathing is usually benign, whereas actual trouble swallowing (dysphagia), pain when swallowing (odynophagia), or any breathing difficulty should prompt faster medical assessment
Evidence-Base Disclosure The published evidence base for AOD-9604 consists predominantly of preclinical research animal models (often rats or mice) and in vitro cell-culture experiments
The authors thank Ferdinand C Breedveld and Geertrui Betgen for invaluable assistance, as well as the subjects and their families for agreeing to participate in this trial
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