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Two groups of factors seem instrumental: endogenous factors (genetic predisposition and cutaneous vasculature) and exogenous factors which may trigger the conditions such as sun exposure, pregnancy, use of oral contraceptives and steroids, ovarian tumours, intestinal parasitic infestation, deranged liver function, use of cosmetics and photosensitizing medications, inflammatory disorders of the skin and stressful events.[] The significance of this condition owing to melanogenesis is due to the fact that it relapses frequently, is difficult to treat, and severely affects social and emotional well-being of patients

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Immunity Immunity 52 , 767781.e766 (2020)

Product Description: Achieve a radiant and youthful complexion with the DermaFirm Glutathione Mist Ampoule & Glutathione Melting Film