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The American Academy of Allergy, Asthma & Immunology outlines three key criteria for diagnosis: Recurrent, multisystem symptoms Laboratory evidence of elevated mast-cell mediators (e.g., tryptase, histamine) Symptom relief when mast-cell activation is blocked or reduced Flushing, itching, gastrointestinal cramps, heart-rate swings, and debilitating fatigue often cycle unpredictablyleading to years of misdiagnoses like IBS, anxiety, or stress. How Mold Makes It Worse Thanks to South Texas long summers, heavy rains, and high humidity, indoor mold is a common and often overlooked issue

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