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The uptake and metabolism of amino acids are aberrantly upregulated in many cancers that display addiction to particular amino acids
Based on these findings, cancer cells dynamically regulate the flux between the two pathways according to their genetic background (e.g., Kras status) and microenvironmental conditions (e.g., oxygen levels and nutrient availability) to maximize survival advantages
This remarkable ability makes glutathione a key player in the body's defense system, helping to maintain cellular integrity and function
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