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Recently, it has been shown that in Crohns disease, the gut-derived bacterium Clostridium innocuum translocated to the mesenteric adipose tissue and modulates its function by inducing M2 macrophage polarization, increasing adipogenesis, and promoting microbial surveillance
124 Conversely, both the C max and AUC of statins decreased by 2870% and 040%, respectively, after GLP-1 RA subcutaneous administration
No increase in serious adverse events or severe hypoglycaemia was observed with the higher dose
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