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The SELECT trial was the first large, randomized study to show that a drug used for obesity could reduce cardiovascular disease, says Isaacs

The results of the reproducibility analysis were expressed using the relative standard deviation (RSD), a statistical measure that evaluates the variability of data points within and between experimental days

Replacing the C-terminal amide of the MT-II scaffold with a hydroxyl group yields a related cyclic peptide with a distinct receptor-selectivity profile, while retaining the lactam-bridged, enzymatically stable architecture

Nitric oxide also plays a role in iron trafficking because it mimics the consequences of iron starvation and triggers iron uptake by cells