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76 Therapeutic strategies therefore aim to remodel the tumor microenvironment and convert these cold lesions into immune-inflamed states
Treatment starts at 0.25 mg weekly for four weeks to improve tolerability, then typically increases to 0.5 mg, with further escalation to 1 mg or 2 mg if needed
It is used in its most concentrated in the heart and skeletal muscles where it plays an important role in energy production and detoxification
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