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The requirements of potential nanocarriers for CNS drug delivery are biodegradability, non-toxic characteristics, scalable synthesis and controlled loading or coupling with hydrophilic or hydrophobic drugs [20, 21]
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The thioredoxin (Trx)-based system is another crucial antioxidant pathway in melanocytes, composed of Trx, thioredoxin reductase (Trx-R), and NADPH
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