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These mutations alter the activity of the encoded enzymes such that instead of converting isocitrate to 2-oxoglutarate (-ketoglutarate), while also generating NADPH, the mutant IDH enzymes reduce 2-oxoglutarate (-ketoglutarate) to 2-hydroxyglutarate (2-HG) while simultaneously oxidizing NADPH to NAPD +
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In early February, Hims took the fight to another level when it announced that it was launching the sale of a compounded semaglutide pill, one clearly meant to compete with Novo Nordisks recently approved Wegovy pill
"Reta" is the colloquial shorthand for retatrutide, widely used in forums, social media, and search queries analogous to "tirz" for tirzepatide and "sema" for semaglutide
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