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Clinical indications include deficiency due to inadequate diet or malabsorption, drug-induced deficiency (for example, from long-term isoniazid or oral contraceptives), and certain inborn errors of metabolism (such as pyridoxine-dependent seizures or sideroblastic anemia)
(September 2007)
Monitor and adjust early If symptoms return before the next dose, review dosing interval and cofactors instead of waiting
Methionine is needed for DNA synthesis and methylation reactions
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