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While PIONEER 6 demonstrated cardiovascular safety (non-inferiority), and the SOUL trial reported significant reductions in MACE, the oral formulation does not yet carry a formal FDA indication for cardiovascular risk reduction in high-risk adults with type 2 diabetes
Throughout treatment, progress is monitored through follow-up visits and ongoing communication
It's less common for Wegovy to be covered
The most severe documented case involved a 35-year-old female who developed rhabdomyolysis while on tirzepatide
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