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Patients over 50 starting GLP-1 therapy should discuss bone health monitoring with their provider, ensure adequate calcium and vitamin D intake, and incorporate weight-bearing exercise into their routine
Willard et al., 2020 Biased and Imbalanced Agonism Willard and colleagues published a detailed pharmacological characterization in JCI Insight in 2020 [2]
Precautions
Todays guidance will no doubt help save lives as cardiovascular disease is still one of the countrys biggest killers. Professor Robert Storey, professor of cardiology at the University of Sheffield, noted that while huge strides had been made in reducing the risk of heart attack and stroke after a cardiovascular event, obesity is associated with harmful inflammation and blood clot risk that is not fully addressed by conventional treatments
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