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Anatomy of the extradural compartments of the lumbar spinal canal
Chronic deficiency may impair tissue repair, metabolic flexibility, and long-term physiologic resilience
It communicates with multiple organs, including the brain, pancreas, stomach, and digestive system to help regulate hunger, blood sugar, and energy balance
It should be noted that, while blood transfusion remains an important therapeutic option in SCD, evidence for its role in management of acute or chronic complications is lacking except for prevention of primary and secondary strokes (Howard, 2016)
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