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Treatment with teplizumab resulted in significantly higher C-peptide AUC levels compared to placebo at week 78 (least-squares mean difference, 0.13 pmol per milliliter
Mild redness, bruising, or swelling at the injection sites is normal and should resolve within a few days
The most common include nausea (reported in 1229% of patients depending on dose), vomiting (513%), diarrhoea (1321%), and constipation (611%), as documented in the SURPASS and SURMOUNT clinical trials
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