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Contact your GP promptly if you experience: Palpitations or a noticeably irregular heartbeat Persistent or severe gastrointestinal symptoms Unexplained dizziness or fainting Yellowing of the skin or eyes, dark urine, or upper abdominal pain (which may indicate liver problems) Worsening of a pre-existing condition, such as elevated blood pressure or blood glucose instability For those seeking structured support with weight management, a GP can refer patients to NHS weight management services, discuss eligibility for pharmacological treatment such as orlistat or semaglutide, and provide access to dietetic or psychological support where appropriate
April 2025: Research found that semaglutide users had a slightly higher risk of developing a serious eye issue compared to people taking other GLP-1 RA drugs
Case Report: Semaglutide-associated depression: a report of two cases [PMID: 37706035] Laboratory literature summary: Case Report: Semaglutide-associated depression: a report of two cases
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