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CSCs possess a strong ability to evade programmed cell death induced by detachment (known as anoikis), allowing them to survive under adverse metastatic conditions characterized by extracellular matrix (ECM) deprivation, which is promoted during chemotherapy or radiotherapy [181]

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Ring-shaped top views of the complexes were also observed upon adsorption to grids without glow discharge, likely due to a preferential adsorption of the complex on these grids (Fig

The clinical evidence for some of these agents (like SGLT2 inhibitors and statins) in improving cardiovascular outcomes is strong, supporting the concept that modulating pathways intertwined with oxidative stress is a viable therapeutic approach