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Trowbridge says that Accutane (isotretinoin) is not available over the counter and requires a prescription from a dermatologist due to its potentially serious side effects, that include birth defects, which is why it is strictly regulated under the iPLEDGE program 20 in the U.S
Wound healing applications may warrant higher doses
Regardless, it is still unknown whether folate synthesized by the human colonic microbiota can substantially affect the bodys general folate status as this has never been sufficiently quantified to date 90,211,233,248,251,277,286,291
Vitamin C, in particular, has been shown to increase the production of white blood cells responsible for fighting off infections
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