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When researchers got their hands on three illegal versions, they found that the counterfeit drugs had low-purity semaglutide, had dosages that exceeded the labeled amount, and one had signs of bacterial contamination
Genome-wide association studies have identified multiple IBD susceptibility loci within IL-23 pathway genes (IL23R, IL12B, JAK2, TYK2, STAT3), providing strong genetic validation for therapeutic targeting
Summary: Ozempic (semaglutide) does not directly lower oestrogen levels through its pharmacological action, but significant weight loss from treatment can indirectly affect oestrogen metabolism by reducing adipose tissue where peripheral oestrogen conversion occurs
Research has yet to confirm if oral options will offer these same benefits
