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Recent studies indicate that by 2030, almost 14% of men and 20% of women around the globe are expected to experience obesity (Federation 2022)
Adding trevogrumab preserved roughly half of that lean loss at lower doses and more than half at higher doses
Next step: larger, well-powered trials in knee OA that prioritize patient-centered outcomes (pain, function, imaging, and time to joint replacement), plus equitable access so these benefits are not limited to the few
At the same time, RS generated by SeC@PA(+) was significantly reduced, proving that Se could eliminate RS in the absence of GSH
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