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The most commonly reported side effects in the Phase 2 trial were gastrointestinal, including nausea, vomiting, diarrhoea, and constipation, which were generally mild to moderate and most prominent during dose escalation
The effect of a dipeptidyl peptidase-4 (DPP-4) inhibitor on -cell glucose sensitivity was calculated by mathematical modeling using data from a mixed meal test and a corresponding isoglycemic intravenous glucose infusion that exactly copied the blood glucose changes during the mixed meal test [17]
In February 2021, the researchers published findings from the STEP 1 trial in The New England Journal of Medicine showing that patients who injected Ozempic (semaglutide) lost close to 15% of their body weight , on average, compared with 2.4% among patients receiving the placebo
By Jace A.
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