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Antisense Oligonucleotide-Mediated Downregulation of IGFBPs Enhances IGF-1 Signaling [PMID: 38189760] Laboratory literature summary: Antisense Oligonucleotide-Mediated Downregulation of IGFBPs Enhances IGF-1 Signaling

Two columns in particular half-life and dosing convention carry a heavy caveat: the figures that circulate for both compounds are vendor and community conventions, not established human pharmacokinetics

Patients with pre-existing diabetic retinopathy should be aware that rapid improvement in blood glucose control can sometimes temporarily worsen retinopathy and should have regular eye monitoring