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doi: 10.1056/nejmoa1910549
2024) and will contribute substantially to our understanding of dysregulation in this regard, in ASD
The circular muscle layer, arranged circumferentially around the gut lumen, mediates segmental contractions that facilitate mixing of luminal contents 22 , whereas the longitudinal layer, aligned parallel to the length of the intestine, contributes to propulsion through coordinated shortening of the gut 23
The mechanism likely involves impaired fear extinction, the process by which the brain learns that a previously threatening stimulus is no longer dangerous
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