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GLP-1 agonists enhance insulin secretion from pancreatic beta cells only when blood glucose levels are elevated, a mechanism termed "glucose-dependent insulinotropic action." This physiological approach reduces the risk of hypoglycemia compared with sulfonylureas or exogenous insulin, though the risk increases when GLP-1 agents are combined with insulin or sulfonylureas, potentially requiring dose adjustments of these medications

Adhering to the discipline of this cadence may take a bit more effort but offers an alternative to the reliance on drugs

Insurance wouldn't cover it, but a coupon from the drug's manufacturer, Eli Lilly, allowed her to get it for just $25