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DMF mediates NRF2-dependent and independent mechanisms on TSS pathway CBS activation DMF activates NRF2, the master regulator for the antioxidative stress response, to regulate the expression of proteins involved in iron hemostasis, and GSH synthesis such as HMOX1, NQO1, FTH, FTL, SLC40A1 in a variety of cellular systems 37
Plusieurs tudes dmontrent le rle du glutathion dans la prvention de certaines maladies et infections, telles que le cancer et le diabte
10.1139/bcb-2018-0189 8
doi: 10.1016/j.neurol.2018.12.006 68 KirbyLJinJCardonaJGSmithMDMartinKAWangJet al
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