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Practical Strategies to Combat Fatigue During Semaglutide Treatment Proper hydration ranks as the single most effective countermeasure: dehydration amplifies both fatigue and nausea during GLP-1 therapy

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Nutrients, 10(9), 1140

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2022 (atherosclerosis RCT): A clinical trial in 157 individuals aged 5875 with metabolic syndrome who received 1 g L-carnitine or placebo twice daily for 6 months found that total cholesterol and LDL cholesterol levels were higher in participants taking L-carnitine

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B12 supplementation may help if levels are low

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