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Longer continuous use may lead to receptor downregulation and diminished returns

Journal of the American College of Nutrition, 27 (5), 547

The weight-loss conversation would be much simpler if we had large, controlled human trials measuring fat-loss outcomes

Mechanistically, we foresee that such effect depends on the ability of CoQ 10 to intercalate within the lipid bilayer and altering cholesterol-dependent PM rigidity and cortical cell softness vs